Common name(S) Deadly nightshade, belladonna, black nightshade, nightshade, sleeping nightshade.
Toxin(s) Atropine and other belladonna alkaloids.
Toxic part(s) Whole plant.
Signs Ingestion causes atropine-like signs-dry mouth, repeated
swallowing efforts, dysphagia, tachycardia, mydriasis, and urinary retention.
Treatment If ingestion was recent, gastric emptying by induction of emesis or lavage is appropriate. Administer activated charcoal and a cathartic. Human literature recommends slow IV administration of physostigmine to effect, that is, until symptoms abate or until cholinergic signs appear. Since belladonna alkaloids have a longer half-life than physostigmine has, repeated doses of physostigmine may be required.